Sculptra 1 vial (367.5 mg)

Sculptra overview

Sculptra 1 vial (367.5 mg) is an injectable implant supplied as a sterile, lyophilized powder intended for soft-tissue restoration and wrinkle correction. It is best known as a biostimulatory filler: rather than creating only immediate “gel volume,” it is used to support gradual improvement in facial volume and contour over the weeks following treatment.

In clinical practice it is used for correction of shallow to deep nasolabial fold contour deficiencies and other facial wrinkles where deeper dermal/subcutaneous injection techniques are appropriate. In some settings, it is also used to address facial fat loss (lipoatrophy) in appropriate patients, under professional guidance.

Composition and how it works

The active component is poly-L-lactic acid (PLLA) microparticles. The vial also contains sodium carboxymethylcellulose and mannitol, which help with suspension and handling once prepared. Before use, the powder must be reconstituted to form a uniform, sterile suspension for injection.

PLLA treatments are typically associated with a progressive, natural-looking change, because the effect is expected to develop gradually after placement. For this reason, Sculptra is generally planned as a course of treatments rather than a single “one-and-done” procedure, with the exact plan tailored to the individual anatomy and goals.

Treatment planning, professional use, and safety notes

Sculptra is intended for professional use only by trained healthcare practitioners. Standard protocols often involve up to several sessions spaced a few weeks apart, with results building over time. Because improvement is expected to be gradual, practitioners typically avoid “overfilling” at the initial session and instead adjust over follow-up visits.

As with any injectable procedure, temporary injection-site effects may occur, such as swelling, bruising, redness, discomfort, or small lumps. Delayed papules or nodules have also been reported and may persist for longer periods in some cases. Sculptra should not be used in patients with hypersensitivity to its components, and treatment should be deferred in areas with active inflammation or infection. It must not be injected into blood vessels; intravascular injection can lead to serious complications, so appropriate technique and anatomical caution are essential.